ANBAR JOURNAL OF AGRICULTURAL SCIENCES

Abstract

This study was conducted to follow the effect of magnetized water on the toxicity of cadmium in the liver of swiss albino mice strain (BULB/C).Four groups of mice were used , 40 female individuals for each group. First group was treated with normal water for 33 days, second group was treated with magnetized water for 33 days, third group was treated with cadmium (100 ppm) dissolved in normal water for 21 days followed with normal water without cadmium for 12 days, and the fourth group was treated with cadmium (100 ppm ) dissolved in magnetized water for 21 days followed with magnetized water without cadmium. At the end of exposures the liver extraction was used for total soluble proteins measurements and enzyme assay. The comparisons of the results between control group and treated groups revealed the following :
A significant increase in ALP and ALT activities in the liver of treated animals with cadmium or magnetized water and a significant decrease in total soluble proteins in the liver of treated animals with cadmium or magnetized water. A significant decrease in acid phosphatase activity in the liver of treated animals with cadmium dissolved in magnetized water. Appearance of a new bands of protein and disappearance of others in groups treated with cadmium on polyacrylamide gel electrophoresis,and a new esterase band appeared in liver of animals treated with cadmium dissolved in normal water .
Accumulated cadmium were 2.06 and 2.24 and 0.1 µ/g wet weight in liver of animals treated with cadmium dissolved in normal water and cadmium dissolved in magnetized water respectively , while the cadmium concentration in control animals was 0.1 µ/g wet weight.