Abstract

In the Study we investigate the effectiveness of interference between honey and antibiotics to Staphylococcus aureus, which one of the most resistant pathogens to antibiotics, and study there sensitivity forward 16 antibiotic and consecutive concentrations of honey, in addition to the interference between honey and antibiotics, and study the effect of honey on total lipids in bacterial cells.
The results of sensitive test shown that, the isolation display variance response to antibiotics which used in this experiment, and also proved the high sensitivity of the isolation toward antibiotics like: Clindamycin, Amikacin and Ciprofloxacin, the most influential antibiotic with inhibition diameters 28, 21 and 20 mm, respectively.
Increasing sensitivity of isolation in direct correlation with the increasing concentration of honey, and the isolation have recorded the maximum inhibition diameter 16.5 mmdisk in concentration 50% of honey, and when examining the interference between honey and antibiotics, results showed evident disparity in their sensitivity to the treatment, depended antibiotic type and honey concentration .
In general the antibiotics activity increasing when the honey concentration is increase for example , the bacterial isolate became sensitive to Amoxillin clavulanic acid in diameters range between 31 and 34 to the treatment of antibiotic and honey wile , the isolate was resist to treatment of antibiotic alone .
On the other hand the result showed effect of honey to change the total lipids, the honey decreasing the lipids in the bacterial cells opposition with concentration of Honey